Inhibiteurs de protease

Protease inhibitors

Abstract

This invention relates to the compound of Formula (I) or a pharmaceutically acceptable salt, hydrate or solvate thereof, which is an inhibitor of cysteine proteases, particularly cathepsin K, and is useful in the treatment of diseases in which inhibition of bone loss or of cartilage degradation is a factor.
L'invention concerne un composé représenté par la formule (I) ou un solvate, un hydrate ou un sel pharmaceutiquement acceptable de celui-ci. Ce composé est un inhibiteur des cystéine protéases, en particulier de la cathepsine K, et il est utile dans le traitement des maladies nécessitant l'inhibition de la perte osseuse ou de la dégradation cartilagineuse.

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Patent Citations (1)

    Publication numberPublication dateAssigneeTitle
    WO-0038687-A1July 06, 2000Smithkline Beecham CorporationProtease inhibitors

NO-Patent Citations (1)

    Title
    See also references of EP 1229914A4

Cited By (8)

    Publication numberPublication dateAssigneeTitle
    EP-1303281-A1April 23, 2003SmithKline Beecham CorporationVerfahren zur behandlung
    EP-1303281-A4February 15, 2006Smithkline Beecham CorpVerfahren zur behandlung
    US-6534498-B1March 18, 2003Smithkline Beecham CorporationProtease inhibitors
    US-6583137-B1June 24, 2003Smithkline Beecham CorporationProtease inhibitors
    US-6596715-B1July 22, 2003Smithkline Beecham CorporationProtease inhibitors
    US-7071184-B2July 04, 2006Smithkline Beecham CorporationProtease inhibitors
    US-7405209-B2July 29, 2008Smithkline Beecham Corporation, Smithkline Beecham P.L.C.Protease inhibitors
    US-7563784-B2July 21, 2009Smithkline Beecham CorporationProtease inhibitors